The cognitive consequences of non-central nervous system (non-CNS) cancer and cancer-related treatments did not become the subject of scientific investigation until recently and is still a growing area of research. Contemporary studies have made it clear that neuropsychology is an integral part of the evaluation and care of individuals with cancer. Today we talk with Michael Parsons, Ph.D., ABPP-CN, about the evaluation of cognitive change due to cancer and cancer-related treatment, factors that influence cognitive decline in these patients, and how interdisciplinary work can benefit these patients.