In this episode, we discuss the long-term cognitive and mental health effects of sport related concussion, which includes an in depth conversation about chronic traumatic encephalopathy (CTE), with Dr. Nyaz Didehbani. Specific topics covered include methodological limitations of the literature on long-term effects of concussion, risk of neurodegenerative diseases from TBI (mild to severe), and CTE history, neuropathology, clinical symptoms, and sociocultural/sociopolitical influences.