INS NYC 2024 Program

Symposium

Symposia 4 Program Schedule

02/15/2024
11:45 am - 01:15 pm
Room: West Side Ballroom - Salon 1

Symposia 4: History of Neuropsychology: Prior Steps & Future Directions


Simposium #4

Origins and Influences of Wada testing

David Loring, Emory University, Atlanta, United States
Kimford Meador, Stanford University, Palo Alto, United States

Category: Epilepsy/Seizures

Keyword 1: test development
Keyword 2: asymmetry

Objective:

Although the pharmacologic inactivation of a vascular territory to transiently inactivate brain function in the distribution of the injected artery was first introduced by Gardner in 1941, Wada initially developed his technique of amobarbital intracarotid amobarbital administration to reduce cognitive side effects of electroconvulsive therapy (ECT) by anesthetizing the language dominate hemisphere during ECT.   Wada introduced the approach of intracarotid amobarbital injection to the Montreal Neurological Institute In 1954 to evaluate cerebral language dominance in epilepsy surgery candidates, which was subsequently modified by Milner to assess the risk of postoperative amnesia using the reversible lesion design to mimic the effects of surgical resection on memory outcome.   This presentation will trace the historical developments of Wada testing and its continuing influence on our understanding of brain-behavior relationship.

Participants and Methods:

Historical review

Results:

Non-empirical presentation

Conclusions:

See above