Poster Session 09 Program Schedule
02/16/2024
03:30 pm - 04:45 pm
Room: Shubert Complex (Posters 1-60)
Poster Session 09: Epilepsy | Oncology | MS | Infectious Disease
Final Abstract #4
Poster Symposium: Neuropsychology in the Era of SARS-CoV-2 — Abstract 3
Cognitive rehabilitation of executive functions and attention in Post-Acute Sequelae of SARS-CoV-2 (PASC): A randomized controlled trial
Jan Stubberud, University of Oslo, Oslo, Norway
Category: Cognitive Intervention/Rehabilitation
Keyword 1: cognitive functioning
Keyword 2: executive functions
Keyword 3: neurocognition
Objective:
Post-Acute Sequelae of SARS-CoV-2 (PASC) is associated with impairments in executive functions (EF) and attention that may have a detrimental effect on everyday functioning, warranting efficient interventions. Goal Management Training (GMT) is a cognitive rehabilitation (CR) protocol for attention and EFs that has received empirical support in other patient groups. The presentation will discuss the efficacy of GMT in improving attention and EFs in adults who experience persistent cognitive deficits in PASC.
Participants and Methods:
In a randomized controlled trial, we will be comparing the efficacy of GMT to a waitlist control condition. At the time of writing, recruitment has not yet started but the study aims to recruit 240 participants aged 18 to 65 years with a history of laboratory- or home-test confirmed, SARS-CoV-2 infection (> 3 months since infection) and perceived attentional and EF difficulties that have lasted for at least two months. Participants will be randomized to either group-based GMT (n = 120) or WL (n = 120). GMT will be internet-delivered to groups of six participants in six two-hour sessions delivered once a week. The primary outcome will be the Behavior Rating Inventory of Executive Function at six months post-treatment. Secondary outcomes include performance-based neurocognitive measures, and questionnaires of cognition, emotional health, quality of life, and fatigue.
Results:
Preliminary findings will be presented at the conference.
Conclusions:
Conclusion: Study findings could contribute to providing an evidence-based treatment option for symptoms that are frequent and debilitating following a prevalent condition. Implications of cognitive rehabilitation in PASC recovery will be discussed.
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