INS NYC 2024 Program

Poster

Poster Session 09 Program Schedule

02/16/2024
03:30 pm - 04:45 pm
Room: Shubert Complex (Posters 1-60)

Poster Session 09: Epilepsy | Oncology | MS | Infectious Disease


Final Abstract #49

Parkinson's Disease Among American Indian and Alaska Native People: A Social Determinants of Health-Informed Systematic Review

Alexandra Hernandez-Vallant, University of New Mexico, Albuquerque, United States
Stephanie Nitschke, Mind Research Network, Albuqueruqe, United States
Kayla Julio, Mind Research Network, Albuquerque, United States
Steven Verney, University of New Mexico, Albuquerque, United States
Sephira Ryman, Mind Research Network, Albuquerque, United States

Category: Medical/Neurological Disorders/Other (Adult)

Keyword 1: Parkinson's disease
Keyword 2: diversity
Keyword 3: social processes

Objective:

American Indian/Alaska Native (AI/AN) communities experience significant health disparities driven by social determinants of health (SDOH). However, little is known about the role of SDOH relevant to Parkinson’s disease (PD) for AI/AN people and the degree to which this contributes to widening health inequities among the AI/AN aging population. Further research is also needed to clarify SDOH related risk and protective factors in PD among AI/AN communities to aid in accurate diagnosis, early treatment, and improved health outcomes. The aim of this systematic review was to summarize the PD literature that includes AI/AN using an SDOH framework to guide future advancements in PD research and clinical care.

Participants and Methods:

We conducted a systematic review using an SDOH framework adapted from Healthy People 2030 to attend to known PD risk and protective factors along with factors relevant to AI/AN health disparities derived from the adapted NIMHD SDOH framework. Variables were extracted from the five adapted Healthy People 2030 domains (economic stability, education access and quality, social and community context, and healthcare access and quality) and a sixth study-derived domain related to PD risk/protective factors (biological and behavioral factors domain). Three electronic databases were searched in June 2023 and peer-reviewed articles based in the United States and published in the English language were included.

Results:

We identified 11 empirical articles that met inclusion criteria and majority used data from preexisting clinical databases (n=7). Three studies included only AI/AN participants, and the remaining studies included AI/AN subsamples (some with five or less participants; n=4). Social and community context was the most frequently included SDOH domain (100%), with race, ethnicity, and gender as the only represented variables, followed by healthcare access and quality variables (n=7) and neighborhood and built environment (n=5). Few studies reported on economic stability (n=2), education access and quality (n=3), and biological and behavioral factors that are relevant to PD risk (n=2).

Conclusions:

Race, ethnicity, and gender, all variables from the social and community context domain, were predominantly represented in the literature reviewed, while other SDOH were underrepresented. SDOH factors rooted in the sociocultural context of AI/AN participants’ lived experience is especially needed to work towards health equity in AI/ANs who are likely disproportionately at risk for PD. Such factors may include social connectedness, racial discrimination, spirituality, and access to and engaging in cultural practices. Similarly, most studies utilized clinical database data and did not report consultation or approval from Tribal council or local area review boards. To this end, community-engaged research led by and with AI/ANs prioritizes community interests and values, are urgently needed to increased health-equity better identifying and treating PD in this population.