INS NYC 2024 Program

Poster	Poster Session 08 Program Schedule 02/16/2024 01:45 pm - 03:00 pm Room: Majestic Complex (Posters 61-120) Poster Session 08: Cognition \| Cognitive Reserve Variables Final Abstract #62 Longitudinal Case Analysis of a Multilingual Patient with Parkinson’s Disease: The Role of Self-Care and Interventions in Cognitive Reserve and Resiliency Daniel Saldana, UCLA Semel Institute, Los Angeles, United States Diomaris Safi, UCLA Semel Institute, Los Angeles, United States Category: MCI (Mild Cognitive Impairment) Keyword 1: Parkinson's disease Keyword 2: cognitive reserve Keyword 3: cognitive functioning Objective: Parkinson’s disease (PD) is a chronic, degenerative disorder that leads to mild neurocognitive impairment (MCI) in approximately 20 to 57% of patients within three to five years from diagnosis. Throughout the course of the disease process, patients with PD are six times more likely to develop dementia than the general population. The disease course follows that approximately 80% of PD patients will develop a major neurocognitive disorder within 20 years of diagnosis, with risk factors including advanced age, cerebrovascular burden, the severity of motor symptoms and specific PD subtype, as well as contributions from comorbid mood diagnoses increasing the conversion risk. Importantly, the literature provides evidence that the MCI stage is an ideal point of time to implement interventions to reduce risk for further conversion into dementia, which impacts patients’ quality of life and life expectancy. This case study takes a look at protective and resiliency factors against neurodegeneration. Participants and Methods: Ms. Sunflowers is a highly educated (master’s degree), trilingual (Spanish, English, Hebrew) with high occupational attainment (i.e., managerial role in healthcare setting). She presents with a history of multiple head injuries and hypoxic events. From a psychological perspective, she has also experienced traumatic events. She has a significant medical history of vascular and metabolic disease. She lives independently and her goal is to maintain her independency for as long as possible. To that end, she has participated in a number of interventions, including physical exercise and individual therapy for mood dysregulation. Additionally, she has strengthened her social engagement through forming community in her environment, practices mindfulness and artistic endeavors (i.e., sculpting, painting, poetry), and maintains an open-mindedness and intellectual curiosity toward alternative interventions for PD (i.e., singing, boxing). Results: Ms. Sunflowers has received four separate neuropsychological evaluations spanning seven years. She was diagnosed with a mild neurocognitive disorder in her first evaluation. Longitudinal analysis of her performance across testing time points revealed generally well-preserved functioning across most domains with continued but stable executive inefficiencies. Conclusions: Engaging in evidence-based interventions can not only improve quality of life but also improve longevity in patients with PD complicated by other medical diagnoses. Importantly, the present case study highlights the need for follow through on evidence-based treatments (as typically offered as part of neuropsychological feedback). This longitudinal case analysis also demonstrates how individual differences may lead to more positive outcomes, particularly as it pertains to individuals of multilingual and multicultural backgrounds.

Poster

02/16/2024
01:45 pm - 03:00 pm
Room: Majestic Complex (Posters 61-120)

Poster Session 08: Cognition | Cognitive Reserve Variables

Final Abstract #62

Longitudinal Case Analysis of a Multilingual Patient with Parkinson’s Disease: The Role of Self-Care and Interventions in Cognitive Reserve and Resiliency

Daniel Saldana, UCLA Semel Institute, Los Angeles, United States
Diomaris Safi, UCLA Semel Institute, Los Angeles, United States

Category: MCI (Mild Cognitive Impairment)

Keyword 1: Parkinson's disease
Keyword 2: cognitive reserve
Keyword 3: cognitive functioning

Objective:

Parkinson’s disease (PD) is a chronic, degenerative disorder that leads to mild neurocognitive impairment (MCI) in approximately 20 to 57% of patients within three to five years from diagnosis. Throughout the course of the disease process, patients with PD are six times more likely to develop dementia than the general population. The disease course follows that approximately 80% of PD patients will develop a major neurocognitive disorder within 20 years of diagnosis, with risk factors including advanced age, cerebrovascular burden, the severity of motor symptoms and specific PD subtype, as well as contributions from comorbid mood diagnoses increasing the conversion risk. Importantly, the literature provides evidence that the MCI stage is an ideal point of time to implement interventions to reduce risk for further conversion into dementia, which impacts patients’ quality of life and life expectancy. This case study takes a look at protective and resiliency factors against neurodegeneration.

Participants and Methods:

Ms. Sunflowers is a highly educated (master’s degree), trilingual (Spanish, English, Hebrew) with high occupational attainment (i.e., managerial role in healthcare setting). She presents with a history of multiple head injuries and hypoxic events. From a psychological perspective, she has also experienced traumatic events. She has a significant medical history of vascular and metabolic disease. She lives independently and her goal is to maintain her independency for as long as possible. To that end, she has participated in a number of interventions, including physical exercise and individual therapy for mood dysregulation. Additionally, she has strengthened her social engagement through forming community in her environment, practices mindfulness and artistic endeavors (i.e., sculpting, painting, poetry), and maintains an open-mindedness and intellectual curiosity toward alternative interventions for PD (i.e., singing, boxing).

Results:

Ms. Sunflowers has received four separate neuropsychological evaluations spanning seven years. She was diagnosed with a mild neurocognitive disorder in her first evaluation. Longitudinal analysis of her performance across testing time points revealed generally well-preserved functioning across most domains with continued but stable executive inefficiencies.

Conclusions:

Engaging in evidence-based interventions can not only improve quality of life but also improve longevity in patients with PD complicated by other medical diagnoses. Importantly, the present case study highlights the need for follow through on evidence-based treatments (as typically offered as part of neuropsychological feedback). This longitudinal case analysis also demonstrates how individual differences may lead to more positive outcomes, particularly as it pertains to individuals of multilingual and multicultural backgrounds.