INS NYC 2024 Program

Poster	Poster Session 06 Program Schedule 02/15/2024 04:00 pm - 05:15 pm Room: Majestic Complex (Posters 61-120) Poster Session 06: Aging \| MCI \| Neurodegenerative Disease - PART 2 Final Abstract #98 Exploring the Association Between Sedentary Behavior, Cardiorespiratory Fitness, and Episodic Memory in Aging. Jessica Stark, The Ohio State University, Columbus, United States Jasmeet Hayes, The Ohio State University, Columbus, United States Matthew Stauder, The Ohio State University, Columbus, United States William Kraemer, The Ohio State University, Columbus, United States Scott Hayes, The Ohio State University, Columbus, United States Category: Aging Keyword 1: aging (normal) Keyword 2: cognitive functioning Objective: As our aging population grows, it is important to identify modifiable variables that can preserve cognition across the lifespan. The goal of this study was to examine the relationships between objective metrics of sedentary behavior, cardiorespiratory fitness, and visual and verbal episodic memory. Participants and Methods: 82 adults ages 18- 86 years were recruited from the Fitness, Aging, Stress, and TBI Exposure Repository (mean age = 50.3 years, sd = 20.6; mean education = 16.8 years, sd = 3.4; 52% female). The ActiGraph GT9X was used to collect metrics of sedentary behavior (percent time sedentary, total sedentary bouts greater than 30 minutes) and standardized neuropsychological tests were used to assess visual and verbal episodic memory. Four hierarchical regressions were conducted to assess the relationships between either percent time sedentary or number of sedentary bouts and two sub-domains of episodic memory: visual and verbal. Demographic variables, cardiorespiratory fitness (peak VO₂), and sedentary behavior (either percent time or total bouts) were included in the models. Results: A main effect of number of sedentary bouts on verbal episodic memory was observed, such that a greater number of sedentary bouts was associated with poorer verbal episodic memory, even after accounting for demographic variables and cardiorespiratory fitness. This relationship did not interact with age. The peak VO₂x sedentary behavior interaction was trending (p = .067), such that those with lower cardiorespiratory fitness had a significant, negative relationship between number of sedentary bouts and verbal episodic memory, whereas those with higher cardiorespiratory fitness had a null relationship. Main effects of cardiorespiratory fitness and percent time sedentary were not significant for verbal episodic memory. For visual episodic memory, there also was a main effect of number of sedentary bouts after accounting for covariates. This relationship did not interact with age or peak VO₂. Main effects of cardiorespiratory fitness and percent time sedentary were not significant for visual episodic memory. However, there was a significant age x peak VO₂ interaction: a significant positive relationship between cardiorespiratory fitness and visual episodic memory was observed for older adults, whereas younger adults had a null relationship. Conclusions: Results revealed that the relationship between number of sedentary bouts and verbal episodic memory was dependent on cardiorespiratory fitness. This suggests that improving cardiorespiratory fitness may be an important target for future interventions focused on maintenance of verbal episodic memory, regardless of age. Greater number of sedentary bouts was also negatively associated with visual episodic memory. Contrasting verbal episodic memory, this relationship was not dependent on cardiorespiratory fitness, suggesting that reducing sedentary bouts may improve visual episodic memory, independent of cardiorespiratory fitness. Additionally, results showed that the relationship between age and visual episodic memory was dependent on cardiorespiratory fitness, suggesting that cardiorespiratory fitness may be important for preserving visual episodic memory in older but not younger adults. Overall, results suggest that the number of sedentary bouts and cardiorespiratory fitness may be relevant modifiable variables to consider for future interventions.

Poster

02/15/2024
04:00 pm - 05:15 pm
Room: Majestic Complex (Posters 61-120)

Poster Session 06: Aging | MCI | Neurodegenerative Disease - PART 2

Final Abstract #98

Exploring the Association Between Sedentary Behavior, Cardiorespiratory Fitness, and Episodic Memory in Aging.

Jessica Stark, The Ohio State University, Columbus, United States
Jasmeet Hayes, The Ohio State University, Columbus, United States
Matthew Stauder, The Ohio State University, Columbus, United States
William Kraemer, The Ohio State University, Columbus, United States
Scott Hayes, The Ohio State University, Columbus, United States

Category: Aging

Keyword 1: aging (normal)
Keyword 2: cognitive functioning

Objective:

As our aging population grows, it is important to identify modifiable variables that can preserve cognition across the lifespan. The goal of this study was to examine the relationships between objective metrics of sedentary behavior, cardiorespiratory fitness, and visual and verbal episodic memory.

Participants and Methods:

82 adults ages 18- 86 years were recruited from the Fitness, Aging, Stress, and TBI Exposure Repository (mean age = 50.3 years, sd = 20.6; mean education = 16.8 years, sd = 3.4; 52% female). The ActiGraph GT9X was used to collect metrics of sedentary behavior (percent time sedentary, total sedentary bouts greater than 30 minutes) and standardized neuropsychological tests were used to assess visual and verbal episodic memory. Four hierarchical regressions were conducted to assess the relationships between either percent time sedentary or number of sedentary bouts and two sub-domains of episodic memory: visual and verbal. Demographic variables, cardiorespiratory fitness (peak VO₂), and sedentary behavior (either percent time or total bouts) were included in the models.

Results:

A main effect of number of sedentary bouts on verbal episodic memory was observed, such that a greater number of sedentary bouts was associated with poorer verbal episodic memory, even after accounting for demographic variables and cardiorespiratory fitness. This relationship did not interact with age. The peak VO₂x sedentary behavior interaction was trending (p = .067), such that those with lower cardiorespiratory fitness had a significant, negative relationship between number of sedentary bouts and verbal episodic memory, whereas those with higher cardiorespiratory fitness had a null relationship. Main effects of cardiorespiratory fitness and percent time sedentary were not significant for verbal episodic memory. For visual episodic memory, there also was a main effect of number of sedentary bouts after accounting for covariates. This relationship did not interact with age or peak VO₂. Main effects of cardiorespiratory fitness and percent time sedentary were not significant for visual episodic memory. However, there was a significant age x peak VO₂ interaction: a significant positive relationship between cardiorespiratory fitness and visual episodic memory was observed for older adults, whereas younger adults had a null relationship.

Conclusions:

Results revealed that the relationship between number of sedentary bouts and verbal episodic memory was dependent on cardiorespiratory fitness. This suggests that improving cardiorespiratory fitness may be an important target for future interventions focused on maintenance of verbal episodic memory, regardless of age. Greater number of sedentary bouts was also negatively associated with visual episodic memory. Contrasting verbal episodic memory, this relationship was not dependent on cardiorespiratory fitness, suggesting that reducing sedentary bouts may improve visual episodic memory, independent of cardiorespiratory fitness. Additionally, results showed that the relationship between age and visual episodic memory was dependent on cardiorespiratory fitness, suggesting that cardiorespiratory fitness may be important for preserving visual episodic memory in older but not younger adults. Overall, results suggest that the number of sedentary bouts and cardiorespiratory fitness may be relevant modifiable variables to consider for future interventions.