Poster Session 06 Program Schedule
02/15/2024
04:00 pm - 05:15 pm
Room: Majestic Complex (Posters 61-120)
Poster Session 06: Aging | MCI | Neurodegenerative Disease - PART 2
Final Abstract #63
Unraveling the Controversy between Napping and Alzheimer's Disease: A Systematic Review
Dongyeon Kim, Shanghai American School Puxi, Shanghai, Korea, Republic of
Paul Lewis, Columbia University Vagelos College of Physicians and Surgeons, New York, United States
Category: Dementia (Alzheimer's Disease)
Keyword 1: dementia - Alzheimer's disease
Keyword 2: aging disorders
Keyword 3: sleep
Objective:
Associations between daytime napping and Alzheimer's disease have been controversial. This systematic review aims to examine the relationship between daytime napping and Alzheimer’s disease and its role in cognition.
Participants and Methods:
A systematic review was conducted following PRISMA guidelines using various iterations of keywords such as “Napping”, “Alzheimer’s Disease”, and “Dementia” in Pubmed, Google Scholar, and PsycInfo. A plethora of useful sources relating to daytime napping and Alzheimer’s disease were found. Of these, (n=73) sources directly discussed daytime napping and its effect on cognitive impairment. I narrowed down to (n=37) sources that specifically focus on the association between napping and cognitive impairment or decline by screening through titles and abstracts. Through assessing full text for eligibility, including a presence of peer review and credibility of the author, (n=13) viable sources that remained that could be used for INTRODUCTION and RESULTS sections.
Results:
These studies included longitudinal, neuroimaging, and cross-sectional studies. Findings from longitudinal studies suggest a potential longitudinal relationship between daytime napping and Alzheimer’s disease in elders compared to participants without excessive daytime napping. Finding from imaging, along with statistical analysis, suggested a potential link between the excessive daytime nappers (1-2 times per week or more) with subsequent accumulation of amyloid deposition, a hallmark of Alzheimer’s disease. A cross-sectional study revealed the connection between nap length and cognitive performance in older adults. The study suggests that long naps (>90 min) was associated with an increased risk of cognitive impairment, while naps of moderate duration ((31–60 min) were associated with better cognitive performance on delayed word recall task (DWR).
Conclusions:
A potential association exists between excessive daytime napping and Alzheimer’s disease. More rigorous studies are needed to further explore the long-term effects of napping on Alzheimer’s disease progression, how napping impacts cognitive function across a wide range of age groups, what causes different frequencies and patterns of napping, and to determine the optimal nap duration for maximizing cognitive benefits.
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