INS NYC 2024 Program

Poster

Poster Session 06 Program Schedule

02/15/2024
04:00 pm - 05:15 pm
Room: Shubert Complex (Posters 1-60)

Poster Session 06: Aging | MCI | Neurodegenerative Disease - PART 2


Final Abstract #20

Memory Focused Cognitive Training for Older Adult Populations With and Without Cognitive Impairment: A CogTale Meta-Analysis

Courtney Chesser, Deakin University, Melbourne, Australia
Benjamin Hampstead, University of Michigan, Ann Arbor, United States
Alex Bahar-Fuchs, Deakin Unviersity, Melbourne, Australia

Category: Aging

Keyword 1: cognitive functioning
Keyword 2: memory training

Objective:

Cognitive-oriented treatments (COT), particularly cognitive training (CT) have been demonstrated to improve cognition in older people with Mild Cognitive Impairment (MCI) and dementia, as well as in cognitively unimpaired older people. Building upon our previous meta-analysis (Bahar-Fuchs et al. 2023) that explored how memory-oriented CT impacted memory in MCI, the current meta-analysis examined this in people on the continuum of cognitive health. In addition, whether there is a difference in the benefits associated with strategy-based, repetition-based or group-based memory training remains unknown.  

Participants and Methods:

We conducted a systematic review using CogTale (Sabates et al. 2021), a novel evidence synthesis tool which semi-automates aspects of the meta-analysis pipeline. The CogTale database was searched for eligible studies. Studies reporting the results of a controlled, memory-oriented CT intervention for cognitively healthy older adults, people with MCI, and people with dementia who reported at least one cognitive outcome were eligible. Multi-domain CT, multicomponent interventions were excluded. Data from eligible studies was extracted into the CogTale platform, and methodological quality scores (Cochrane Risk of Bias, PEDro) were computed for each studyRandom effects inverse variance meta-analysis was performed for all outcomes reported by a minimum of three studies, and confidence in the effect estimates was computed based on heterogeneity, precision, and risk of bias.  

Results:

After searching the CogTale Database, 47 studies (30 reporting any strategy, 17 individually reported) that underwent full-text review were eligible. Small to moderate effects were found for auditory-verbal working memory. Studies using any memory strategy (k= 30) showed small significant effects for auditory verbal memory.  When studies focused on Mnemonic Strategy Training (MST) (k=18) were analysed separately, findings were no longer significant for auditory verbal memory outcomes. The confidence in these findings was, however, low. Across older adult populations findings differed. For studies using memory interventions in MCI populations (k = 25), significant findings were found the broad outcome of memory and specifically auditory-verbal memory. In studies that included  healthy older adult (k = 15) and people living with dementia (k =7), the findings on memory specific outcome did not remain and were not-significant.

 

Conclusions:

Memory-oriented CT studies in older adult populations are associated with improvements in auditory-verbal working memory and memory. When considering only memory-oriented CT studies that included any memory strategy, improvements were still seen for auditory verbal memory. When considering only studies that used MST, MST was not associated with any improvements in outcomes. To better understand whether MST is a beneficial component of memory-oriented CT, further high-quality research is necessary across older adult populations.