INS NYC 2024 Program

Poster	Poster Session 06 Program Schedule 02/15/2024 04:00 pm - 05:15 pm Room: Shubert Complex (Posters 1-60) Poster Session 06: Aging \| MCI \| Neurodegenerative Disease - PART 2 Final Abstract #29 Similarities in dispersion of cognitive profile among individuals with subjective or amnestic mild cognitive impairment Hsin-Te Chang, Department of Psychology, College of Science, Chung Yuan Christian University, Taoyuan, Taiwan Mau-Sun Hua, Department of Psychology, College of Science, National Taiwan University, Taipei, Taiwan Ko-Ting Chen, Department of Neurosurgery, Chang Gung Memorial Hospital-Linkou Branch, Taoyuan, Taiwan Pai-Yi Chiu, Department of Neurology, Show Chwan Memorial Hospital, Changhua, Taiwan Li-Chung Lin, Department of Psychology, College of Science, Chung Yuan Christian University, Taoyuam, Taiwan Category: MCI (Mild Cognitive Impairment) Keyword 1: mild cognitive impairment Keyword 2: dementia - Alzheimer's disease Objective: Detecting the subtle cognitive symptoms in the early stage of Alzheimer’s disease (AD) is challenging. The subtle cognitive changes may be difficult to be detected using an inter-individual comparison approach. We aimed to develop an intra-individual approach of analyzing cognitive profile in the early stages of AD. Participants and Methods: We compared cognitive profiles among a sample of 1,124 individuals comprising groups of individuals with subjective cognitive impairment (SCI) (n = 576), mild cognitive impairment (MCI) (n = 268), or dementia of AD type (DAT) (n = 280). A disperse score (DS) using the standard deviation of standardized scores across each cognitive domain including memory, executive function, attention, language, and visuospatial functions was compared across the groups. Results: The SCI and MCI groups displayed same levels of DS which were higher than the DAT group. The major contributions to the DS in the SCI and MCI groups were lower memory and executive functions. The standardized scores on the cognitive tasks were higher among individuals with SCI than those among MCI patients. Conclusions: This study highlighted the importance of comprehensive neuropsychological assessment and an intra-individual approach to detect the potential cognitive changes in the early stage of AD.

Poster

02/15/2024
04:00 pm - 05:15 pm
Room: Shubert Complex (Posters 1-60)

Poster Session 06: Aging | MCI | Neurodegenerative Disease - PART 2

Final Abstract #29

Similarities in dispersion of cognitive profile among individuals with subjective or amnestic mild cognitive impairment

Hsin-Te Chang, Department of Psychology, College of Science, Chung Yuan Christian University, Taoyuan, Taiwan
Mau-Sun Hua, Department of Psychology, College of Science, National Taiwan University, Taipei, Taiwan
Ko-Ting Chen, Department of Neurosurgery, Chang Gung Memorial Hospital-Linkou Branch, Taoyuan, Taiwan
Pai-Yi Chiu, Department of Neurology, Show Chwan Memorial Hospital, Changhua, Taiwan
Li-Chung Lin, Department of Psychology, College of Science, Chung Yuan Christian University, Taoyuam, Taiwan

Category: MCI (Mild Cognitive Impairment)

Keyword 1: mild cognitive impairment
Keyword 2: dementia - Alzheimer's disease

Objective:

Detecting the subtle cognitive symptoms in the early stage of Alzheimer’s disease (AD) is challenging. The subtle cognitive changes may be difficult to be detected using an inter-individual comparison approach. We aimed to develop an intra-individual approach of analyzing cognitive profile in the early stages of AD.

Participants and Methods:

We compared cognitive profiles among a sample of 1,124 individuals comprising groups of individuals with subjective cognitive impairment (SCI) (n = 576), mild cognitive impairment (MCI) (n = 268), or dementia of AD type (DAT) (n = 280). A disperse score (DS) using the standard deviation of standardized scores across each cognitive domain including memory, executive function, attention, language, and visuospatial functions was compared across the groups.

Results:

The SCI and MCI groups displayed same levels of DS which were higher than the DAT group. The major contributions to the DS in the SCI and MCI groups were lower memory and executive functions. The standardized scores on the cognitive tasks were higher among individuals with SCI than those among MCI patients.

Conclusions:

This study highlighted the importance of comprehensive neuropsychological assessment and an intra-individual approach to detect the potential cognitive changes in the early stage of AD.