INS NYC 2024 Program

Poster	Poster Session 05 Program Schedule 02/15/2024 02:30 pm - 03:45 pm Room: Majestic Complex (Posters 61-120) Poster Session 05: Neuropsychiatry \| Addiction/Dependence \| Stress/Coping \| Emotional/Social Processes Final Abstract #63 Psychiatric Symptomatology in Veterans with MCI and History of TBI Sarah Langdon, Palo Alto University, Palo Alto, United States Peter Louras, Stanford University School of Medicine, Stanford, United States Adriana Savettiere, Palo Alto University, Palo Alto, United States J. Kaci Fairchild, Stanford University School of Medicine, Stanford, United States Category: Aging Keyword 1: brain injury Keyword 2: mild cognitive impairment Objective: The population of older adults is increasing at an unprecedented rate worldwide. Risk for morbidity increases with age, including risk for traumatic brain injury (TBI). Research shows TBI can lead to neurological and functional impairment and increase the potential for long-term psychiatric conditions. TBI is also associated with an increased risk for mild cognitive impairment (MCI), yet little is known about the relationship to psychiatric symptomatology in this population. Therefore, the aim of the current study was to explore the psychiatric profiles of older adults with MCI, with and without TBI histories. Participants and Methods: The sample consisted of 107 older adults (mean age = 70.83 ±9.02) with MCI. Participants were predominantly male (94%), White (78%), and educated (more than 53% had a bachelor’s degree or higher). Ten percent (n=11) reported a history of TBI. Psychiatric assessments included the Mini-International Neuropsychiatric Interview, the Barratt Impulsiveness Scale, Penn State Worry Questionnaire, and the Geriatric Depression Scale. Group differences were assessed using independent t-tests and Pearson Chi-Square tests. Results: Participants with TBI history were more likely than those without TBI to have experienced a hypomanic episode (X² = 6.95, p = 0.009), and show significantly higher scores on the Barratt subscales of Motor Impulsivity (t = -2.212, p = 0.029), Cognitive Complexity (t = -2.394, p = 0.018), and Non-Planning Impulsiveness (t = -1.991, p = 0.049). No other significant differences were found between the two groups. Conclusions: Our results demonstrate that in a sample of older adults with MCI, those with TBI history were more likely to have experienced a hypomanic episode, act without thinking, and focus on the present moment rather than engage in future planning. Our findings support prior research demonstrating TBI history is associated with an increased potential for psychiatric conditions and functional impairment, yet research exploring TBI history in an MCI population is limited. These results provide insight into the consequences of TBI history in an aging population, and aid in separating symptoms of MCI from that of TBI. Future studies should aim to replicate these findings and explore psychiatric symptomatology following different types and severity levels of TBI in MCI populations.

Poster

02/15/2024
02:30 pm - 03:45 pm
Room: Majestic Complex (Posters 61-120)

Poster Session 05: Neuropsychiatry | Addiction/Dependence | Stress/Coping | Emotional/Social Processes

Final Abstract #63

Psychiatric Symptomatology in Veterans with MCI and History of TBI

Sarah Langdon, Palo Alto University, Palo Alto, United States
Peter Louras, Stanford University School of Medicine, Stanford, United States
Adriana Savettiere, Palo Alto University, Palo Alto, United States
J. Kaci Fairchild, Stanford University School of Medicine, Stanford, United States

Category: Aging

Keyword 1: brain injury
Keyword 2: mild cognitive impairment

Objective:

The population of older adults is increasing at an unprecedented rate worldwide. Risk for morbidity increases with age, including risk for traumatic brain injury (TBI). Research shows TBI can lead to neurological and functional impairment and increase the potential for long-term psychiatric conditions. TBI is also associated with an increased risk for mild cognitive impairment (MCI), yet little is known about the relationship to psychiatric symptomatology in this population. Therefore, the aim of the current study was to explore the psychiatric profiles of older adults with MCI, with and without TBI histories.

Participants and Methods:

The sample consisted of 107 older adults (mean age = 70.83 ±9.02) with MCI. Participants were predominantly male (94%), White (78%), and educated (more than 53% had a bachelor’s degree or higher). Ten percent (n=11) reported a history of TBI. Psychiatric assessments included the Mini-International Neuropsychiatric Interview, the Barratt Impulsiveness Scale, Penn State Worry Questionnaire, and the Geriatric Depression Scale. Group differences were assessed using independent t-tests and Pearson Chi-Square tests.

Results:

Participants with TBI history were more likely than those without TBI to have experienced a hypomanic episode (X² = 6.95, p = 0.009), and show significantly higher scores on the Barratt subscales of Motor Impulsivity (t = -2.212, p = 0.029), Cognitive Complexity (t = -2.394, p = 0.018), and Non-Planning Impulsiveness (t = -1.991, p = 0.049). No other significant differences were found between the two groups.

Conclusions:

Our results demonstrate that in a sample of older adults with MCI, those with TBI history were more likely to have experienced a hypomanic episode, act without thinking, and focus on the present moment rather than engage in future planning. Our findings support prior research demonstrating TBI history is associated with an increased potential for psychiatric conditions and functional impairment, yet research exploring TBI history in an MCI population is limited. These results provide insight into the consequences of TBI history in an aging population, and aid in separating symptoms of MCI from that of TBI. Future studies should aim to replicate these findings and explore psychiatric symptomatology following different types and severity levels of TBI in MCI populations.