INS NYC 2024 Program

Poster	Poster Session 04 Program Schedule 02/15/2024 12:00 pm - 01:15 pm Room: Majestic Complex (Posters 61-120) Poster Session 04: Neuroimaging \| Neurostimulation/Neuromodulation \| Teleneuropsychology/Technology Final Abstract #66 Utilization of Standardized Regression-Based Change Scores to Compare Remote and In-Person Cognitive Testing Performance in Older Adults Lauren Latham, Wake Forest University School of Medicine, Winston Salem, United States Suzanne Craft, Wake Forest University School of Medicine, Winston Salem, United States Stephen Rapp, Wake Forest University School of Medicine, Winston Salem, United States James Bateman, Wake Forest University School of Medicine, Winston Salem, United States Maryjo Cleveland, Wake Forest University School of Medicine, Winston Salem, United States Sam Rogers, Wake Forest University School of Medicine, Winston Salem, United States Benjamin Williams, Wake Forest University School of Medicine, Winston Salem, United States Mia Yang, Wake Forest University School of Medicine, Winston Salem, United States Bonnie Sachs, Wake Forest University School of Medicine, Winston Salem, United States Category: Teleneuropsychology/ Technology Keyword 1: assessment Keyword 2: teleneuropsychology Keyword 3: dementia - Alzheimer's disease Objective: Use standardized regression-based (SRB) change indices to examine the frequency of declines or improvements in scores over 1-year (e.g., scores that exceed various SRB cut-points) on available UDSv3 neuropsychological tests administered either remotely or in person at follow up. Participants and Methods: All included participants (N=230) (Mean age: 68.6 (7.8) years; education: 16.3 (2.3) years; 71% female; 86% White) were from the Wake Forest ADRC and were cognitively normal (as defined by a CDR of 0) at both baseline and first follow-up assessments. Follow-up testing at approximately 1 year (range: 344-629 days, mean: 420 days) was completed either in-person (N=121) or remotely via phone or video (N=109). SRB change index scores were calculated for each participant using the formulas developed by Kiselica et al. (2020) for the following tests: Craft Story immediate and delayed verbatim recall, semantic fluency (animals and vegetables), verbal fluency (F and L), and number span forwards and backwards. We used chi-squared analyses to compare the frequency of scores falling outside of specified SRB thresholds (greater than or less than 1.282, 1.645, or 1.96) for in-person versus remote follow up assessments. Additionally, the mean SRB change scores for in-person and remote follow up assessments are reported and compared via t-tests. Results: Chi-squared analysis revealed no significant differences in the frequency of SRB change scores for in-person versus remote follow up assessments at any of the three SRB cut-points. An exploratory analysis of mean SRB change scores via independent samples t-tests revealed that digit span backward performance was slightly higher for remote (M = 0.21, SD = 0.98) versus in-person (M = -0.07, SD = 0.82) testing (p = 0.02). There were not significant differences between remote and in-person follow up assessments for any of the other tests. Conclusions: SRB change indices accounting for baseline scores, practice effects, reliability, regression to the mean, age, race, education, gender, and test re-test interval indicate that there are not significant differences in performance on selected UDSv3 tests for in-person versus remote follow-up testing performance, with the exception of digit span backward for which remote testing performance is higher than in-person testing performance. These findings suggest that remote cognitive testing in this sample of cognitively unimpaired older adults is generally a viable alternative to in-person testing, though there may be a need for caution in the interpretation of remotely administered digit span backward.

Poster

02/15/2024
12:00 pm - 01:15 pm
Room: Majestic Complex (Posters 61-120)

Poster Session 04: Neuroimaging | Neurostimulation/Neuromodulation | Teleneuropsychology/Technology

Final Abstract #66

Utilization of Standardized Regression-Based Change Scores to Compare Remote and In-Person Cognitive Testing Performance in Older Adults

Lauren Latham, Wake Forest University School of Medicine, Winston Salem, United States
Suzanne Craft, Wake Forest University School of Medicine, Winston Salem, United States
Stephen Rapp, Wake Forest University School of Medicine, Winston Salem, United States
James Bateman, Wake Forest University School of Medicine, Winston Salem, United States
Maryjo Cleveland, Wake Forest University School of Medicine, Winston Salem, United States
Sam Rogers, Wake Forest University School of Medicine, Winston Salem, United States
Benjamin Williams, Wake Forest University School of Medicine, Winston Salem, United States
Mia Yang, Wake Forest University School of Medicine, Winston Salem, United States
Bonnie Sachs, Wake Forest University School of Medicine, Winston Salem, United States

Category: Teleneuropsychology/ Technology

Keyword 1: assessment
Keyword 2: teleneuropsychology
Keyword 3: dementia - Alzheimer's disease

Objective:

Use standardized regression-based (SRB) change indices to examine the frequency of declines or improvements in scores over 1-year (e.g., scores that exceed various SRB cut-points) on available UDSv3 neuropsychological tests administered either remotely or in person at follow up.

Participants and Methods:

All included participants (N=230) (Mean age: 68.6 (7.8) years; education: 16.3 (2.3) years; 71% female; 86% White) were from the Wake Forest ADRC and were cognitively normal (as defined by a CDR of 0) at both baseline and first follow-up assessments. Follow-up testing at approximately 1 year (range: 344-629 days, mean: 420 days) was completed either in-person (N=121) or remotely via phone or video (N=109). SRB change index scores were calculated for each participant using the formulas developed by Kiselica et al. (2020) for the following tests: Craft Story immediate and delayed verbatim recall, semantic fluency (animals and vegetables), verbal fluency (F and L), and number span forwards and backwards. We used chi-squared analyses to compare the frequency of scores falling outside of specified SRB thresholds (greater than or less than 1.282, 1.645, or 1.96) for in-person versus remote follow up assessments. Additionally, the mean SRB change scores for in-person and remote follow up assessments are reported and compared via t-tests.

Results:

Chi-squared analysis revealed no significant differences in the frequency of SRB change scores for in-person versus remote follow up assessments at any of the three SRB cut-points. An exploratory analysis of mean SRB change scores via independent samples t-tests revealed that digit span backward performance was slightly higher for remote (M = 0.21, SD = 0.98) versus in-person (M = -0.07, SD = 0.82) testing (p = 0.02). There were not significant differences between remote and in-person follow up assessments for any of the other tests.

Conclusions:

SRB change indices accounting for baseline scores, practice effects, reliability, regression to the mean, age, race, education, gender, and test re-test interval indicate that there are not significant differences in performance on selected UDSv3 tests for in-person versus remote follow-up testing performance, with the exception of digit span backward for which remote testing performance is higher than in-person testing performance. These findings suggest that remote cognitive testing in this sample of cognitively unimpaired older adults is generally a viable alternative to in-person testing, though there may be a need for caution in the interpretation of remotely administered digit span backward.