INS NYC 2024 Program

Poster

Poster Session 04 Program Schedule

02/15/2024
12:00 pm - 01:15 pm
Room: Shubert Complex (Posters 1-60)

Poster Session 04: Neuroimaging | Neurostimulation/Neuromodulation | Teleneuropsychology/Technology


Final Abstract #24

Verbal and Nonverbal Memory Validity of Computerized Cognitive Assessment: CNS-VS Vital Signs, in a Veteran Population

Lisa Cruz, Stanford Medicine, VA Palo Alto, Palo Alto, United States
Lauren Meier, Virginia Polytechnic Institute and State University, Blacksburg, United States
Nicole Walker, Stanford Medicine, VA Palo Alto, Palo Alto, United States
Michelle Madore, VA Palo Alto, Stanford Medicine, Palo Alto, United States

Category: Teleneuropsychology/ Technology

Keyword 1: computerized neuropsychological testing
Keyword 2: psychometrics
Keyword 3: validity (performance or symptom)

Objective:

Traditional paper-and-pencil based neuropsychological assessments tend to be costly, time-consuming, and more prone to human error relative to computerized methods. This is concerning, given that prompt and accurate identification of individuals at risk for cognitive impairment is crucial. Computerized neuropsychological testing has become increasingly prevalent, especially during the COVID-19 pandemic. CNS-VS Vital Signs (CNS-VS-VS) is a neurocognitive and behavioral health assessment technology that is used across clinical and research settings. While a number of studies have investigated the validity of CNS-VS-VS in other populations (e.g., healthy controls, TBI patients), there is limited knowledge regarding the validity of CNS-VS within adult Veteran populations.  Therefore, the current study goal was to examine the concurrent validity of the CNS-VS verbal and nonverbal memory domains among adult Veterans. It was predicted that high concurrent validity of CNS-VS verbal and nonverbal memory domains would be found, compared with traditional neuropsychological tests recognized to measure similar constructs.

Participants and Methods:

The sample was comprised of 63 adult Veterans (M age=48, SD=13, male 57%) who were undergoing baseline assessment prior to receiving transcranial magnetic stimulation as treatment for depression. The majority of participants reported being White (55.6%), followed by Asian (3.2%), Black (3.2%), Hispanic (1.6%), and multi-ethnic (4.8%) identities. Participants were administered a range of commonly used traditional neuropsychological measures as well as the computerized CNS-VS. The CNS-VS assesses seven cognitive domains, including verbal and visual memory, which were analyzed in the current study. The traditional assessments of verbal and nonverbal memory that were presently examined were: California Verbal Learning Test-3 (CVLT-3) and Brief Visuospatial Memory Test-Revised (BVMT-R), respectively. Spearman’s correlation analyses were utilized to examine the relationships and validity between CVLT-3 and CNS-VS verbal memory, and BVMT-R and CNS-VS nonverbal memory.

Results:

Regarding verbal memory, significant positive correlations were found between CVLT-3 and CNS-VS for:  immediate cued recall (r =0.35, p =0.01), delayed free recall (r =0.39, p =0.005), delayed cued recall (r =0.36, p =0.01), and recognition (r =0.34, p=0.01). Regarding nonverbal memory, significant positive correlations were found between BVMT-R and CNS-VS for: total recall (r =0.29, p =0.46), delayed recall (r=0.36, p=0.01), and recognition (r=0.36, p=0.009). No significant correlations were found for verbal memory total recall and immediate free recall, nor nonverbal memory immediate recall (ps>0.05).

Conclusions:

In adult Veterans, the CNS-VS verbal and nonverbal memory domains were found to have satisfactory concurrent validity when compared with well-established neuropsychological measures. Despite weak-to-moderate concurrent rates (0.2-0.4 range), the majority of aspects of the CNS-VS verbal and nonverbal assessments (e.g., immediate cued recall, etc.) were significantly correlated with traditional measures. Analyses may have been affected by sample size underpowering, suggesting the need for additional validation studies. Future research is warranted to examine all CNS-VS domains and their psychometric properties, and explore how they and other computerized cognitive tools relate to ecological and patient outcomes. Overall, the current findings support the use of CNS-VS to assess verbal and nonverbal memory abilities, which is notable considering that computerized assessments are a viable alternative to costly and time-consuming, person-administered traditional exams.