INS NYC 2024 Program

Poster	Poster Session 03 Program Schedule 02/15/2024 09:30 am - 10:40 am Room: Shubert Complex (Posters 1-60) Poster Session 03: Neurotrauma \| Neurovascular Final Abstract #81 Working Memory Multicomponent Model Outcomes in Individuals with Traumatic Brain Injury: Systematic Review and Meta-Analysis Bar Lambez, Bar-Ilan University, Ramat-Gan, Israel Eli Vakil, Bar-Ilan University, Ramat-Gan, Israel Philippe Azouvi, AP-HP, GH Paris Saclay, Hôpital Raymond Poincaré, service de Médecine Physique et de Réadaptation, Garches, France Claire Vallat-Azouvi, University of Paris-8-Saint-Denis, Saint-Denis, France Category: Acquired Brain Injury (TBI/Cerebrovascular Injury and Disease - Adult) Keyword 1: working memory Keyword 2: executive functions Keyword 3: traumatic brain injury Objective: Traumatic Brain Injury (TBI) poses a growing health concern, often leading to cognitive impairments, particularly in working memory (WM). Previous reviews have explored WM impairments in individuals with TBI, but they often focus on specific injury severities and WM model components. This meta-analysis aims to examine the impact of varying TBI severities on all components of Baddeley's multi-component model, using objective WM outcome measures. Participants and Methods: Following PRISMA guidelines, a systematic review and meta-analysis were conducted, searching Google Scholar, PubMed, and PsycNET for studies with objective WM measures. Multiple meta-analyses were performed to compare the effects of TBI severity on different WM components. Twenty-four peer-reviewed articles published in English were included, mostly employing cross-sectional designs. Results: Findings indicate that TBI significantly impairs WM in general as well as all components of Baddeley's model. The Central Executive component exhibited the greatest average effect size. Two severity categories, mild-moderate and moderate- severe, were identified. Analyses showed a consistent medium-large effect size of impairment across injury severity, with the 'moderate-severe' category demonstrating the largest average effect size. Evaluation of injury severity interaction with WM components displayed greater deficit in CE as severity increases, but similar moderate effect size, for deficit in slave system components. Similarly, CE effect was found in the flexibility domain of Executive Function. Episodic buffer was found to have a larger moderate effect size in moderate-severe severity. Conclusions: These findings enhance our understanding of WM deficits in individuals with varying severities of TBI, highlighting the importance of assessing and treating the various components of WM in routine clinical practice and intervention planning.

Poster

02/15/2024
09:30 am - 10:40 am
Room: Shubert Complex (Posters 1-60)

Poster Session 03: Neurotrauma | Neurovascular

Final Abstract #81

Working Memory Multicomponent Model Outcomes in Individuals with Traumatic Brain Injury: Systematic Review and Meta-Analysis

Bar Lambez, Bar-Ilan University, Ramat-Gan, Israel
Eli Vakil, Bar-Ilan University, Ramat-Gan, Israel
Philippe Azouvi, AP-HP, GH Paris Saclay, Hôpital Raymond Poincaré, service de Médecine Physique et de Réadaptation, Garches, France
Claire Vallat-Azouvi, University of Paris-8-Saint-Denis, Saint-Denis, France

Category: Acquired Brain Injury (TBI/Cerebrovascular Injury and Disease - Adult)

Keyword 1: working memory
Keyword 2: executive functions
Keyword 3: traumatic brain injury

Objective:

Traumatic Brain Injury (TBI) poses a growing health concern, often leading to cognitive impairments, particularly in working memory (WM). Previous reviews have explored WM impairments in individuals with TBI, but they often focus on specific injury severities and WM model components. This meta-analysis aims to examine the impact of varying TBI severities on all components of Baddeley's multi-component model, using objective WM outcome measures.

Participants and Methods:

Following PRISMA guidelines, a systematic review and meta-analysis were conducted, searching Google Scholar, PubMed, and PsycNET for studies with objective WM measures. Multiple meta-analyses were performed to compare the effects of TBI severity on different WM components. Twenty-four peer-reviewed articles published in English were included, mostly employing cross-sectional designs.

Results:

Findings indicate that TBI significantly impairs WM in general as well as all components of Baddeley's model. The Central Executive component exhibited the greatest average effect size. Two severity categories, mild-moderate and moderate- severe, were identified. Analyses showed a consistent medium-large effect size of impairment across injury severity, with the 'moderate-severe' category demonstrating the largest average effect size. Evaluation of injury severity interaction with WM components displayed greater deficit in CE as severity increases, but similar moderate effect size, for deficit in slave system components. Similarly, CE effect was found in the flexibility domain of Executive Function. Episodic buffer was found to have a larger moderate effect size in moderate-severe severity.

Conclusions:

These findings enhance our understanding of WM deficits in individuals with varying severities of TBI, highlighting the importance of assessing and treating the various components of WM in routine clinical practice and intervention planning.