INS NYC 2024 Program

Poster

Poster Session 02 Program Schedule

02/15/2024
08:00 am - 09:15 am
Room: Majestic Complex (Posters 61-120)

Poster Session 02: Aging | MCI | Neurodegenerative Disease - PART 1


Final Abstract #91

The role of objective and subjective prospective memory reports in everyday functioning in Mild Cognitive Impairment and Alzheimer’s disease

Jordan Kozuki, California State University, Fresno, Fresno, United States
Summer Herrera, California State University, Fresno, Fresno, United States
Angela Hickman, California State University, Fresno, Fresno, United States
Chris Miller, California State University, Fresno, Fresno, United States
David Lent, California State University, Fresno, Fresno, United States
Ellen Woo, California State University, Fresno, Fresno, United States

Category: MCI (Mild Cognitive Impairment)

Keyword 1: memory: prospective
Keyword 2: everyday functioning

Objective:

Prospective memory (PM), which involves remembering to execute a future action, is impacted by Alzheimer’s disease (AD). PM can be assessed using subjective ratings by the participants and a significant other, in addition to objective measurements. This study examined the use of subjective and objective PM measures in predicting everyday functioning in healthy older controls, Mild Cognitive Impairment (MCI), and AD.

Participants and Methods:

Participants included 58 healthy older controls, 65 persons with MCI, and 18 individuals with AD. Subjective reports of PM included both participant and informant ratings on the Prospective-Retrospective Memory Questionnaire (PRMQ). Additionally, an objective PM task was completed during the neuropsychological assessment. Simple PM was measured by asking participants to remember to execute a single action- to request a pill after each neuropsychological task performed. Complex PM was measured by asking participants to request a specific number of pills depending on whether a memory or non-memory test was just completed. Real world functioning was assessed using the Everyday Cognition Scales (E-Cog), which includes five dimensions: language, memory, executive functioning, visual-spatial/perceptual abilities and attention.

Results:

Regression analyses revealed that objective PM (both simple and complex) predicted everyday memory in healthy older controls and MCI. Additionally, the informant PM reports predicted everyday executive functioning in MCI.

Conclusions:

Our results indicated that in cognitively healthy older adults, objective measurements of PM alone were useful in predicting everyday functioning. When mild cognitive deficits are present, both objective measurements and informant observations play roles in predicting everyday functioning.