| Poster | Poster Session 02 Program Schedule
02/15/2024
08:00 am - 09:15 am
Room: Shubert Complex (Posters 1-60)
Poster Session 02: Aging | MCI | Neurodegenerative Disease - PART 1
Final Abstract #56
Perceived Stress and Cognitive Decline in Older Adults in 4-year Follow-Up: Which Aspect of Perceived Stress is Important?
Ji Soo Lee, Institute of Human Genomic Study, College of Medicine, Korea University, Seoul, Korea, Republic of
Soriul Kim, Institute of Human Genomic Study, College of Medicine, Korea University, Seoul, Korea, Republic of
Hyun Kim, Columbia University Irving Medical Center, Manhattan, United States
Seung Ku Lee, Institute of Human Genomic Study, College of Medicine, Korea University, Seoul, Korea, Republic of
Chol Shin, Institute of Human Genomic Study, College of Medicine, Korea University, Seoul, Korea, Republic of
Category: Aging
Keyword 1: aging (normal)
Keyword 2: emotional processes
Keyword 3: cognitive functioning
Objective:
Stress is very common in older adults. Exposure to acute and chronic stress is known to adversely affect cognitive function in late life, and it plays a crucial role in the development of both physical and psychological health problems including cognitive decline, sleep disorders, depression, and anxiety. In terms of stress, people with higher levels of lack of perceived self-efficacy within stress showed worse cognitive performance. Despite the importance of stress and its subfactors having different effects on cognitive function in late life, longitudinal studies explored the relationships between stress, its subfactors, and cognitive decline are absent. Thus, this study aimed to examine whether especially lack of perceived self-efficacy impacts cognitive decline independent of depressive symptoms.
Participants and Methods:
Two thousand one hundred seventy-eight healthy community-dwelling adults aged 50 years or older at baseline (mean age = 62.16, SD = 5.93) completed the Perceived Stress Scale (PSS-10), Beck Depression Inventory, demographic surveys, and neuropsychological tests twice from 2015 to 2022 (mean age difference = 3.91, SD = 0.58). The perceived helplessness scale (PH) consisted of the negative-worded questions and the lack of perceived self-efficiency scale (LPSE) consisted of the positive-worded questions. For the PSS total score and further analysis, LPSE was reversely coded. During the neuropsychological testing, memory function was measured with immediate and delayed recall, and recognition, and language, complex attention, and executive function domains were measured.
Results:
Perceived stress total score was associated with recognition decline (β = -0.045, p = 0.001), which became nonsignificant after Bonferroni correction. The subscale perceived helplessness showed a positive association with language domain change (β = 0.052, p = 0.020); however, two subtests of language domain, phonemic and category fluency tests, became insignificant after Bonferroni correction (β = 0.047, p= 0.035, β = 0.028, p= 0.199, respectively). Lastly, the subscale lack of perceived self-efficacy was significantly associated with memory domain decline, especially in immediate recall (β = -0.068, p= 0.001). Two subtests of the immediate recall domain, logical memory and visual reproduction immediate recall tests, remained significant after Bonferroni correction (β = -0.058, p = 0.006, β = -0.053, p = 0.010, respectively).
Conclusions:
Results of the study demonstrated that within perceived stress, lack of perceived self-efficacy is associated with memory decline, especially immediate recall among older adults. This result suggests that the lack of perceived self-efficacy might be an important factor in increasing stress and cognitive decline in late life.
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