INS NYC 2024 Program

Symposium	Symposia 13 Program Schedule 02/16/2024 03:30 pm - 04:55 pm Room: West Side Ballroom - Salon 1 Symposia 13: Neuropsychological Research and Clinical Applications with Culturally and Linguistically Diverse Populations Simposium #4 Association between cognitive domain scores and informant-rated cognitive decline across Hispanic/Latino/a/e/x and non-Hispanic white older adults Emily Briceno, University of Michigan, Ann Arbor, United States Lisa Lewandowski-Romps, University of Michigan, Ann Arbor, United States Nelda Garcia, University of Michigan, Ann Arbor, United States Steven Heeringa, University of Michigan, Ann Arbor, United States Lewis Morgenstern, University of Michigan, Ann Arbor, United States Category: Inclusion and Diversity/Multiculturalism Keyword 1: diversity Keyword 2: multiculturalism Keyword 3: dementia - Alzheimer's disease Objective: It is unknown whether cognitive test scores are equivalently associated with informant-rated cognitive decline across culturally and linguistically diverse older adult populations. We examined the association between cognitive domain scores on the Harmonized Cognitive Assessment Protocol (HCAP) and informant-rated cognitive decline in a harmonized population-based sample of Hispanic/Latino/a/e/x (H/L) and non-H/L (NHW) older adults. Participants and Methods: We harmonized data from the Harmonized Cognitive Assessment Protocol (HCAP) sub-study of the Health and Retirement Study (HRS) with the Brain Attack Surveillance in Corpus Christi-Cognitive (BASIC-C). The HRS-HCAP is a nationally representative sample of adults 65+ and the BASIC-C is a community-based study of adults 65+ in Nueces County, Texas that is approximately 60% H/L. Both studies utilized the HCAP neuropsychological assessment with demographically-adjusted (age, education, sex/gender, race/ethnicity) domain scores for memory, attention/executive function, language, and global cognitive performance (GCP), and unadjusted visuospatial and orientation scores, as per HRS-HCAP study methods. The Informant Questionnaire of Cognitive Decline in the Elderly (IQCODE) was used as a measure of informant-rated cognitive decline for both studies. We performed a series of regressions in the full sample and in the H/L and NHW groups separately to examine the degree to which cognitive domain scores were associated with IQCODE scores, sequentially adjusting for demographics (age, sex/gender, education) and study membership. Results: The harmonized sample included 609 H/L respondents (age M= 74.7 years, education M = 9.0 years, 61% women) and 2,333 NHW adult respondents (age M = 76.8 years, education M = 13.4 years, 58% women). Informants for H/L participants were younger, had fewer years of education, were more likely to be female and a child of the respondent compared to NHW informants. Cognitive domain scores explained less variance in IQCODE scores in the H/L compared to the NHW group (Memory: r²= 0.02 H/L; r²= 0.21 NHW; Attention/executive functioning r²= 0.02 H/L; r²= 0.18 NHW; language r²=0.06 H/L; r²= 0.10 NHW; Orientation: r² = 0.04 H/L; r²= 0.08 NHW; Visuospatial r²= 0.02 H/L; r²= 0.07 NHW; GCP r² = 0.04 H/L; r² = 0.26 NHW). In fully-adjusted models in the full sample, ethnicity was a unique predictor of IQCODE scores for all cognitive domains (all p’s < .0001). Conclusions: We found consistently weaker relationships between cognitive domain scores and informant-rated cognitive decline in H/L compared to NHW older adults. These findings suggest measurement differences in cognitive assessment and/or informant ratings of decline across culturally and linguistically diverse older adult populations and warrant future measurement research.

Symposium

02/16/2024
03:30 pm - 04:55 pm
Room: West Side Ballroom - Salon 1

Symposia 13: Neuropsychological Research and Clinical Applications with Culturally and Linguistically Diverse Populations

Simposium #4

Association between cognitive domain scores and informant-rated cognitive decline across Hispanic/Latino/a/e/x and non-Hispanic white older adults

Emily Briceno, University of Michigan, Ann Arbor, United States
Lisa Lewandowski-Romps, University of Michigan, Ann Arbor, United States
Nelda Garcia, University of Michigan, Ann Arbor, United States
Steven Heeringa, University of Michigan, Ann Arbor, United States
Lewis Morgenstern, University of Michigan, Ann Arbor, United States

Category: Inclusion and Diversity/Multiculturalism

Keyword 1: diversity
Keyword 2: multiculturalism
Keyword 3: dementia - Alzheimer's disease

Objective:

It is unknown whether cognitive test scores are equivalently associated with informant-rated cognitive decline across culturally and linguistically diverse older adult populations. We examined the association between cognitive domain scores on the Harmonized Cognitive Assessment Protocol (HCAP) and informant-rated cognitive decline in a harmonized population-based sample of Hispanic/Latino/a/e/x (H/L) and non-H/L (NHW) older adults.

Participants and Methods:

We harmonized data from the Harmonized Cognitive Assessment Protocol (HCAP) sub-study of the Health and Retirement Study (HRS) with the Brain Attack Surveillance in Corpus Christi-Cognitive (BASIC-C). The HRS-HCAP is a nationally representative sample of adults 65+ and the BASIC-C is a community-based study of adults 65+ in Nueces County, Texas that is approximately 60% H/L. Both studies utilized the HCAP neuropsychological assessment with demographically-adjusted (age, education, sex/gender, race/ethnicity) domain scores for memory, attention/executive function, language, and global cognitive performance (GCP), and unadjusted visuospatial and orientation scores, as per HRS-HCAP study methods. The Informant Questionnaire of Cognitive Decline in the Elderly (IQCODE) was used as a measure of informant-rated cognitive decline for both studies. We performed a series of regressions in the full sample and in the H/L and NHW groups separately to examine the degree to which cognitive domain scores were associated with IQCODE scores, sequentially adjusting for demographics (age, sex/gender, education) and study membership.

Results:

The harmonized sample included 609 H/L respondents (age M= 74.7 years, education M = 9.0 years, 61% women) and 2,333 NHW adult respondents (age M = 76.8 years, education M = 13.4 years, 58% women). Informants for H/L participants were younger, had fewer years of education, were more likely to be female and a child of the respondent compared to NHW informants. Cognitive domain scores explained less variance in IQCODE scores in the H/L compared to the NHW group (Memory: r²= 0.02 H/L; r²= 0.21 NHW; Attention/executive functioning r²= 0.02 H/L; r²= 0.18 NHW; language r²=0.06 H/L; r²= 0.10 NHW; Orientation: r² = 0.04 H/L; r²= 0.08 NHW; Visuospatial r²= 0.02 H/L; r²= 0.07 NHW; GCP r² = 0.04 H/L; r² = 0.26 NHW). In fully-adjusted models in the full sample, ethnicity was a unique predictor of IQCODE scores for all cognitive domains (all p’s < .0001).

Conclusions:

We found consistently weaker relationships between cognitive domain scores and informant-rated cognitive decline in H/L compared to NHW older adults. These findings suggest measurement differences in cognitive assessment and/or informant ratings of decline across culturally and linguistically diverse older adult populations and warrant future measurement research.