A fundamental challenge to much of the research in neuropsychology (and the behavioral sciences broadly) continues to be a lack of representativeness in the theory, hypotheses, and (critically) sampling in case-control studies. Increased collaboration and data sharing creates novel perspectives and opportunities to increase the diversity and representativeness of our work through team science. With 5 subgroups, 220 investigators across 16 countries, Enhancing Neuroimaging and Genetics Meta-analysis (ENIGMA-TBI) provides a model for addressing critical these issues in the field that directly affect study reproducibility. ENIGMA fosters team science which diversifies the voices involved in leading science and addresses a critical issue regarding the make-up of the participants contributing to our knowledge base. Dr Frank Hillary discusses the importance of open science and study representativeness to address problems with stud reproducibility. Dr. Maheen Adamson then discusses work examining culture, sex and gender differences in TBI outcome work. Dr. Emily Dennis then discusses ENIGMA-U, a recent online and free teaching opportunity to increase access to the neuroscience training and mentorship. ENIGMA-U launched officially on September 2, 2022, and to date, a total of 738 students from 76 countries have enrolled. Finally, Dr. Elisabeth Wilde, a founding member of ENIGMA-TBI, will serve as Discussant for the symposium. The goals of this symposium are to use one example of collaborative, open science (ENIGMA-TBI) to address issues of inequity in our science and training.
