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Podcast Episode 158: Intraoperative Brain Mapping – A Conversation With Drs. Vigneswaran Veeramuthu and Dave Sabsevitz

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Overview

This episode is a discussion with Drs. David Sabsevitz and Veeramuthu Vigneswaran about intraoperative brain mapping. We highlight topics such as the meaning and evolution of the term “eloquent cortex,” localized versus distributed models of brain functioning, aggressiveness versus conservatism of neurosurgeons during resections, the “onco-functional balance,” electrocorticography and stereo EEG procedures, the Wada procedure, the clinical and functional utility of brain mapping, the availability of brain mapping to people of lower SES, neuropsychologists’ role in educating patients and families, cognitive testing during the mapping procedure, and NeuroMapper.
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Instructors & Credentials

Dr. David Sabsevitz

David S. Sabsevitz, PhD, ABPP

Dr. David Sabsevitz is a practicing neuropsychologist and associate professor at Mayo Clinic in Jacksonville, Florida. He has a primary appointment in the Department of Psychiatry and Psychology and a joint appointment in the Department of Neurosurgery. He is board certified by the American Board of Professional Psychology in clinical neuropsychology and specializes in the evaluation and treatment of adults with neurological, and neuropsychiatric disorders. His clinical interests involve onco-epilepsy with focus on the pre-surgical evaluation of brain tumor and epilepsy patients, functional brain mapping, and extra- and intraoperative brain mapping to assist surgical planning in these patient populations. He has numerous publications in peer reviewed scientific journals and is widely recognized for developing innovative brain mapping techniques for awake brain tumor and epilepsy surgery. Dr. Sabsevitz is also very involved in teaching and education and lectures regularly at both the regional and national level.
Dr. Vigneswaran Veeramuthu

Vigneswaran Veeramuthu, PhD

Dr. Vigneswaran Veeramuthu currently serves as a resident Consultant Clinical Neuropsychologist (Adult and Pediatrics) at Thomson Hospital Kota Damansara, Malaysia. He completed his doctoral training with a PhD in Clinical Neuropsychology (Neurosurgery) from University of Malaya in 2016, a clinical fellowship at Hawaii Pacific Neuroscience Institute (2013), and recently a clinical observation at the Department of Neurosurgery, University of California San Francisco (2023). His clinical and research interest lies predominantly in the area of neuropsychological evaluation, presurgical planning, intraoperative brain mapping, advance neuroimaging and rehabilitative interventions in neurological surgery (brain tumors and epilepsy predominantly) and disorders of consciousness.

Disclosure(s)

The authors have no relevant relationships to disclose.

Learning Objectives

Following this activity, participants will be able to:

  1. Define and describe the concepts of eloquent and non-eloquent cortex.
  2. Discuss risks and advantages of brain mapping for patients with particular neurological disorders.
  3. Apply the information from this episode in clinical work with patients who have epilepsy or brain tumors and who may need neurosurgery.

Course Information

Target Audience Introductory
Credit Hours 1.5 hours
Cost & Refund Policy INS Members: $30
Non-Members: $37.50
Refund Policy: This podcast is not eligible for refunds. Users will have two attempts to pass the quiz. If they do not pass, they may re-purchase the test and try again.
Availability January 3, 2024
Note: The CE course for this podcast will be released on this date.
You may obtain CE credit for this podcast at any time after it is released. Content will be retired approximately 3 years after the live date.

References

  • Domingo, R. A., Vivas-Buitrago, T., De Biase, G., Middlebrooks, E. H., Bechtle, P. S., Sabsevitz, D. S., Quiñones-Hinojosa, A., & Tatum, W. O. (2021). Intraoperative Seizure Detection During Active Resection of Glioblastoma Through a Novel Hollow Circular Electrocorticography Array. Operative Neurosurgery, 21(2), E147–E152. https://doi.org/10.1093/ons/opab110
  • Drane, D. L., Pedersen, N. P., Sabsevitz, D. S., Block, C., Dickey, A. S., Alwaki, A., & Kheder, A. (2021). Cognitive and Emotional Mapping With SEEG. Frontiers in Neurology, 12. https://doi.org/10.3389/fneur.2021.627981
  • Freund, B. E., Feyissa, A. M., Khan, A., Sirven, J. I., Grewal, S. S., Sabsevitz, D., Moniz-Garcia, D., Quinones-Hinojosa, A., & Tatum, W. O. (2023). Enhanced sensitivity of electrocorticography during awake craniotomy using a novel circular grid electrode. Journal of Neuro-Oncology, 165(2), 313–320. https://doi.org/10.1007/s11060-023-04495-0
  • Koay, J. M., Michaelides, L., Moniz-Garcia, D. P., Quinones-Hinojosa, A., Chaichana, K., Almeida, J. P., Gruenbaum, B. F., Sherman, W. J., & Sabsevitz, D. S. (2024). Repeated surgical resections for management of high-grade glioma and its impact on quality of life. Journal of Neuro-Oncology, 167(2), 267–273. https://doi.org/10.1007/s11060-024-04600-x
  • Martín-Fernández, J., Gabarrós, A., & Fernandez-Coello, A. (2022). Intraoperative Brain Mapping in Multilingual Patients: What Do We Know and Where Are We Going? Brain Sciences, 12(5), 560. https://doi.org/10.3390/brainsci12050560
  • Ortiz, K. J., Hawayek, M. I., Middlebrooks, E. H., Sabsevitz, D. S., Garcia, D. P., Quinones-Hinojosa, A., & Chaichana, K. L. (2020). Intraoperative Direct Stimulation Identification and Preservation of Critical White Matter Tracts During Brain Surgery. World Neurosurgery, 146, 64–74. https://doi.org/10.1016/j.wneu.2020.10.100
  • ReFaey, K., Tripathi, S., Bhargav, A. G., Grewal, S. S., Middlebrooks, E. H., Sabsevitz, D. S., Jentoft, M., Brunner, P., Wu, A., Tatum, W. O., Ritaccio, A., Chaichana, K. L., & Quinones-Hinojosa, A. (2020). Potential differences between monolingual and bilingual patients in approach and outcome after awake brain surgery. Journal of Neuro-Oncology, 148(3), 587–598. https://doi.org/10.1007/s11060-020-03554-0
  • Roland, J. L., Hacker, C. D., & Leuthardt, E. C. (2020). A Review of Passive Brain Mapping Techniques in Neurological Surgery. Neurosurgery, 88(1), 15–24. https://doi.org/10.1093/neuros/nyaa361
    Seidel, K., Szelényi, A., & Bello, L. (2022). Intraoperative mapping and monitoring during brain tumor surgeries. Handbook of Clinical Neurology, 133–149. https://doi.org/10.1016/b978-0-12-819826-1.00013-2
  • Suarez-Meade, P., Marenco-Hillembrand, L., Prevatt, C., Murguia-Fuentes, R., Mohamed, A., Alsaeed, T., Lehrer, E. J., Brigham, T., Ruiz-Garcia, H., Sabsevitz, D., Middlebrooks, E. H., Bechtle, P. S., Quinones-Hinojosa, A., & Chaichana, K. L. (2020). Awake vs. asleep motor mapping for glioma resection: a systematic review and meta-analysis. Acta Neurochirurgica, 162(7), 1709–1720. https://doi.org/10.1007/s00701-020-04357-y

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